Paroxysmal Supraventricular Tachycardia Following Ondansentron Intravenous Administration: A Case Report
Abstract
Ondasentron is selective serotonin 5-HT3 receptor antagonist. It is widely used as the drug of choice for preventing nausea and vomiting associated with chemotheraphy and post-surgery. This drug become more popular because it’s superior efficacy and minimal side effect. Although cardiovascular adverse effect caused by ondansentron administration is rare, some cardiovascular events have been reported, from atrial fibrillation to fatal ventricular tachycardia. This case reports paroxysmal supraventricular tachycardia in male 23 years old following administration of 4 mg intravenous ondansentronDownloads
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References
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2. Chandrakala R, Vijayashankara CN, Kumar KK, Sarala N. Ondansentron induced fatal ventricular tahcycardia. Indian J Pharmacol 2008;40(4): 186-187.
3. Kasinath NS, Malak O, Tetzlaff J. Atrial fibrillation after ondansetron for the prevention and treatment of postoperative nausea and vomiting: a case report.Can J Anaesth 2003;50(3):229-31
4. Moazzam MS,Nasreen F, Bano S, Amir SH. Symptomatic sinus bradycardia: A rare adverse effect of intravenous ondansentron. Saudi J Anaesth 2011;5(1):96-97.
5. Baguley WA, Hay WT, Mackie KP, Cheney FW, Cullen BF. Cardiac Dysrhythmias Associated with the Intravenous Administration of Ondansetron and Metoclopramide. Anesth Analg 1997; 84:1380-1.
6. Saxena PR, Villalon CM. Cardiovascular effects of serotonin agonists and antagonists. J Cradiovasc Pharmacol 1990;15(7):17–34.
7. Kuryshev YA, Brown AM, Wang L, Benedict CR, Rampe D. Interactions of the 5-hydroxytryptamine 3 antagonists class of antiemetic drugs with human cardiac ion channels. J Pharmacol Exp Ther 2000;295:614–20.
8. Waxman K, Shoemaker WC, Lippman M. Cardiovascular Effects of Anesthetic Induction with Ketamine. Anesth Analg 1980;59:355-358.
9. Craven R, Alkhafaji R. Ketamine in Anaesthetic Practice. {cited: Desember 2014}. Available from : http://www.frca.co.uk/article.aspx?articleid=100644.
Published
2015-12-04
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How to Cite
Hoetama, E. (2015). Paroxysmal Supraventricular Tachycardia Following Ondansentron Intravenous Administration: A Case Report. Indonesian Journal of Cardiology, 36(1), 34-7. https://doi.org/10.30701/ijc.v36i1.439
Section
Case Reports
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